Remeron 7 5 mg more sedating dating someone who was sexually abused as a child

Caution is indicated in administering Mirtazapine Orally Disintegrating Tablets to elderly patients (see PRECAUTIONS and DOSAGE AND ADMINISTRATION).The mean elimination half-life of mirtazapine after oral administration ranges from approximately 20 to 40 hours across age and gender subgroups, with females of all ages exhibiting significantly longer elimination half-lives than males (mean half-life of 37 hours for females vs. The disposition of mirtazapine was studied in patients with varying degrees of renal function.Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24; there was a reduction in risk with antidepressants compared to placebo in adults aged 65 and older.

Anyone considering the use of Mirtazapine Orally Disintegrating Tablets or any other antidepressant in a childor young adult must balance this risk with the clinical need.Patients of all ages who are started on antidepressant therapy should be monitored appropriately and observed closely for clinical worseningor unusual changes in behavior.Families and caregivers should be advised of the need for close observation and communication with the prescriber.data from human liver microsomes indicate that cytochrome 2D6 and 1A2 are involved in the formation of the 8-hydroxy metabolite of mirtazapine, whereas cytochrome 3A is considered to be responsible for the formation of the N-desmethyl and N-oxide metabolite.Mirtazapine has an absolute bioavailability of about 50%.

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